CHARACTERISTICS OF PATIENTS WITH NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND CORONARY PLAQUE EROSION

Abstract

The article discusses the results of a study conducted to clarify the characteristics of patients with myocardial infarction with non-ST-segment elevation (NSTEMI) and coronary plaque erosion. A total of 136 patients diagnosed with NSTEMI who were in stable condition were examined. All patients have a medical history, a standard 12-lead ECG was performed, a troponin T test was performed, a general blood test, C-reactive protein, creatine phosphokinase (CPK) enzyme, lipid spectrum parameters were determined, and optical computed tomography (OCT) was performed. The average troponin T level was 0.65±0.17 ng/ml. Males made up 64.7% and females 35.3%. Plaque erosion was observed in 47.1% of cases, plaque rupture in 37.5% of cases, and calcified plaque in 15.4% of cases. 2 groups were formed: Group I - 64 patients with plaque erosion, group II - 72 patients without plaque erosion (51 patients with plaque rupture + 21 patients with calcified plaque). In group I patients, hypertension (P<0.001), diabetes mellitus (P=0.03) and chronic kidney disease (P=0.03) were less common, a relatively high hemoglobin level (P=0.01), fewer leukocytes (P=0.04) and a better lipid profile were determined. In group I, the level of CRP was 49.4% lower (P=0.04), and the activity of CPK was 38.4% lower (P=0.05). Identifying a group of patients with NSTEMI-ACS with a high probability of plaque erosion can facilitate the distribution of patients and provide an opportunity for individual therapy.