ETIOLOGICAL STRUCTURE OF INFECTIOUS COMPLICATIONS IN CANCER PATIENTS

Abstract

The article presents data on microbiological monitoring of inflammatory complications developing in patients with breast cancer. In order to study the etiological structure of infectious complications in breast cancer, a bacteriological study of samples taken from 40 woman with breast cancer was conducted, and similar data from 10 healthy people in the control group were presented for comparative assessment. In biological fluids of cancer patients, such types of microorganisms as K.pneumoniae, E.coli, etc. were studied and studies were conducted in the direction of identifying markers that could be characteristic of possible complications. At the same time, only in the main group of examined patients there are associations of microorganisms with the presence of Klebsiella spp and Staphylococcus spp., and associations represented by a combination of Escherichia coli / Klebsiella spp. The remaining associations of microorganisms did not exceed 5%, for example, a combination of Pseudomonas spp. / Enterococcus spp. more often it was determined only in 2.5% of patients. In order to identify and prevent infectious complications, as well as to reduce the toxic effect of cytostatics on the intestinal microbiocenosis and mucous membrane, it may be considered appropriate to evaluate changes in the composition of the gastrointestinal tract microbiocenosis in patients receiving treatment.