EVALUATION OF ASTHENIC SYMPTOMS IN PATIENTS WITH SARS-CoV-2 INFECTION

Abstract

The article presents information on asthenic symptoms detected in 172 patients aged 31 to 65 years who had recovered from COVID-19, as well as changes observed in them at 6 and 12 months after the illness. Observations have shown that in patients experiencing asthenic syndrome after COVID-19, sleep disorders, autonomic symptoms, and other neurological manifestations are more pronounced.In the first six months, gait disturbances were recorded in 54.7±3.8% of patients, olfactory impairment in 23.8±3.2%, taste impairment in 14.5±2.7%, memory impairment in 66.3±3.6%, attention problems in 27.9±3.4%, and sensory impairments in 45.9±3.8%. By the 12th month, these symptoms had significantly decreased, being observed in 24.4±3.3% (t=6.06; P<0.001), 13.4±2.6% (t=2.54; P<0.05), 6.4±1.9% (t=0.48; P>0.05), 33.7±3.6% (t=6.40; P<0.001), 17.4±2.9% (t=2.34; P<0.05), and 20.3±3.1% (t=5.23; P<0.001) of patients, respectively.The obtained results indicate the need for a comprehensive study of the determinants and predictors of post-COVID-19 asthenic syndrome, as well as the identification and investigation of these factors both in risk groups and other patient populations for differentiation purposes.