CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS AND RESULTS OF TREATMENT OF MULTIPLE SCLEROSIS

Abstract

The article presents information about the clinical and epidemiological characteristics and results of treatment of multiple sclerosis in the population of the city of Baku. In the period from 2013 to 2020, 559 residents of the city of Baku with multiple sclerosis were involved in the study. Of these, 392 (70.1%) patients were women and 167 (29.9%) men. The disease was diagnosed based on the 2010 McDonald criteria. All patients underwent a standard clinical and neurological examination, health status assessment according to the disability scale (EDSS), MRI of the brain and spinal cord, visual evoked potentials, biochemical and enzyme immunoassays of blood and cerebrospinal fluid. Parametric and nonparametric methods were used for statistical analysis. It was revealed that in terms of the prevalence of multiple sclerosis, the city of Baku can be classified as a medium-risk zone. The incidence rate of multiple sclerosis remained generally stable from 2013 to 2019. It was found that the majority of patients had a relapsing phenotype of multiple sclerosis, which is characterized by a younger age of patients and a positive reaction to disease-modifying drugs.