CERVICAL SCREENING OF WOMEN RECOVERED COVID-19

Abstract

The article presents the results of a study conducted to identify the characteristics of the cervix in women who have recovered from COVID-19. The study examined changes in the objective parameters of the cervix in women who had severe COVID-19 (vaginal discharge, elasticity of the vaginal wall, epithelial integrity, moisture of the mucous membranes, pH of vaginal contents, cytological type, vaginal contents), and also studied the relationship with laboratory data. It was established that the severe form of COVID-19 causes disturbances in the cervix in the form of changes in the amount and deterioration of the structure of vaginal discharge, a feeling of dryness in the external genital area, decreased elasticity of the vaginal walls, and thinning of the epithelial layer. Cytological data indicate the presence of estrogen deficiency and an increase in the number of cases of fungal infection. Among the studied signs, a strong correlation was revealed between C-reactive protein and the pH of the vaginal contents (r=0.70), D-dimer and vaginal contents (r=0.71), procalcitonin and vaginal contents (r=0.70), procalcitonin and vaginal discharge (r=0.73), oxygen saturation and cytological type (r=0.72), oxygen saturation and vaginal contents (r=0.71). According to the authors, the pathogenetic mechanisms of post-COVID-19 with changes in local immunity and the consequences of distress form the prerequisites for local changes in the cervix with the risk of post-Covid cervical transformation.