THE MORPHOLOGICAL FEATURES OF SIALOLITHIASIS IN THE CONTEXT OF BENIGN AND MALIGNANT TUMORS OF THE SALIVARY GLAND

Abstract

The article provides information ab\out research conducted to identify the factors causing the formation of stones in salivary glands. The study utilized 20 tissue samples from salivary glands, encompassing both benign and malignant tumors with biomineral formations. For a more profound understanding of the pathogenesis of calcifications in structurally altered tissues, histological, immunohistochemical analyses (utilizing markers for acute and chronic inflammation, as well as to detect the initiation of apoptosis), and microelement analysis of sialoliths were conducted.
It was found that the formation of sialolithiasis in the presence of a tumorous process occurs due to structural tissue rearrangement amid inflammatory processes, changes in pH levels, and mineral deposition in a specific sequence.