THE INFLUENCE OF ENDOLYMPHATIC DRUG THERAPY ON THE FUNCTIONAL INDEXES IN PATIENTS WITH LOWER EXTREMITIES DIABETIC ANGIOPATHY AND DIABETIC FOOT SYNDROME

Abstract

The research covers 105 patients with lower extremities diabetic angiopathy (LEDA) of II-IV stages and diabetic foot syndrome (DFS), divided into 2 groups: 1 (control) – 60 patients treated with conventional (surgical and conservative) methods, 2 main – 45 patients treated with 196-day course of endolymphatic drug therapy (EDT) anticoagulant, desagregant, antibacterial, enzyme inhibiting, lymph stimulating and detoxicating drugs.
The drugs were administered with minimal one time or daily doses once a day together with 40-60 ml/h infusion into a lymph vessel on foot or shank during 3-14 days, depending on stage of LEDA and severity of DFS. All patients underwent instrumental (rheovaso-, thermography, ultrasound dopplerography) examinations of lower extremities blood circulation to determine stage of LEDA, the level of main vessels occlusion to compare the results of treatment.
The use of EDT in LEDA and DFS improves functional indexes of peripheric blood circulation, microcirculation and tissue metabolism, reduces inflammation and builds up restoration, healing of trophical ulcers and postoperative wounds, and reliably improves the results of complex treatment.