HEMORHEOLOGY AND HEMOSTASIS IN ACUTE PHLEBOTHROMBOSIS OF THE LOWER EXTREMITIES

Abstract

The article presents the results of a study conducted to investigate the relationship between the main parameters of blood rheology and indicators of the hemostasis system in acute phlebothrombosis of the lower extremities. The study is based on the results of clinical and laboratory examinations of 89 patients with acute occlusive phlebothrombosis of the lower extremities (non-embolic form). The diagnosis was confirmed by ultrasound compression duplex angioscanning. The main rheological parameters of blood and hemostasis parameters were evaluated after diagnosis and before the initiation of anticoagulant therapy. To determine the baseline values of the studied parameters, 25 practically healthy individuals were examined. It has been established that in acute phlebothrombosis of the lower extremities, connections are formed between the rheological properties of blood and the hemostasis system. The identified patterns allow for the personalization of thrombolytic and disaggregate therapy for acute phlebothrombosis of the lower extremities, depending on the indicators of blood rheology and hemostasis.