BRUGADA SYNDROME: ITS CLINICAL ASPECTS AND THE PLACE IN CAUSES OF SUDDEN CARDIAC DEATHS

Abstract

Sudden cardiac deaths is one of the most pressing topics in forensic medicine, and the cause of death can be various heart pathologies. Among these pathologies, Brugada syndrome (BS) is in the first place. The article provides information on the clinic and diagnosis of BS with reference to various world literature. The issue of forensic medical examination of sudden cardiac deaths caused as a result of this pathology was also touched upon. BS is more common among young people who look completely healthy and have no complaints. It is characterized by transient partial or complete blockade of the right branch of the His bundle, elevation of the ST segment in right thoracic conductions, and recurrent paroxysmal polymorphic ventricular tachycardia. Although the etiology of the disease is unknown, the presence of genetic factors has been confirmed. The clinical manifestations of BS depend on the degree of damage of the sodium channels and the type of mutation in the SCN5A gene located on 3rd chromosome. The main goal is to diagnose the patient in time and start treatment as soon as possible. Therefore, the article pays special attention to the diagnosis of the disease.