THE ROLE OF METABOLIC AND IMMUNOLOGICAL DISORDERS IN THE DEVELOPMENT OF CHRONIC HEPATITIS C

Authors

  • J.P. Isayev Azerbaijan Medical University
  • R.R. Baylarova Azerbaijan Medical University
  • V.N. Javadzade Azerbaijan Medical University
  • B.A. Valiyev Azerbaijan Medical University

DOI:

https://doi.org/10.34921/amj.2022.3.006

Keywords:

xronik hepatit C, qaraciyər steatozu, qaraciyər fibrozu, qaraciyərin qeyri-alkohol mənşəli piy distrofiyası

Abstract

The article provides information about the study of the impact of metabolic and immuno­logical disorders on chronic viral hepatitis C (CHC). 126 patients with CHC were under observation. Progres­sive fatty degeneration of the liver – grade III steatosis – was detected mainly in patients with F3 and F4 stages of fibrosis, in 33.3% and 42.9% of cases, respectively. The results showed that metabolic disorders significantly aggravated the course of CHC, and a correlation was observed between the degree of steatosis and the stages of fibrosis. The direct correlation was found between the frequency of diabetes mellitus in CHC patients and the stages of fibrosis; Diabetes mellitus was diagnosed in 73.3% of patients with stages F3-4. Changes in the levels of CD118+ and CD119+ - an increasing number and activity, can be proposed as the immunological criterion for predicting severe liver fibrosis.

Downloads

Download data is not yet available.

Downloads

Published

2022-09-30

How to Cite

Isayev , J., Baylarova , R., Javadzade , V., & Valiyev , B. (2022). THE ROLE OF METABOLIC AND IMMUNOLOGICAL DISORDERS IN THE DEVELOPMENT OF CHRONIC HEPATITIS C. Azerbaijan Medical Journal, (3), 37–44. https://doi.org/10.34921/amj.2022.3.006

Issue

No. 3 (2022)

Section

CLINICAL RESEARCH

License

Copyright (c) 2022 Azerbaijan Medical Journal

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.