ELECTRON MICROSCOPIC PICTURE OF THE ADENOHYPOPHYSIS IN PERITONITIS OF STAPHYLOCOCCAL ORIGIN

Abstract

The article presents information about research work carried out to study the electron microscopic features of morphofunctional changes that occur in adenocytes of the adenohypophysis during peritonitis of staphylococcal origin.
The object of the study was the pituitary gland of adult white male rats weighing 180-200 grams. Experimental animals were divided into 2 – control and main groups, 10 animals were included in the control group and 30 animals in the main group. During the study, electron microscopic and morphometric research methods were used.
An electron microscopic examination of the pituitary gland on the 2nd day of the study is characterized by vacuolization of most organelles and a relative decrease in the morphometric parameters of adenocytes, while at later stages of the study (5th and 15th days), they are characterized by sharp destruction and necrosis of cells and a significant decrease in their sizes. The obtained results can be evaluated as a general reaction of glandular cells to a staphylococcal infection introduced into the abdominal cavity – endogenous intoxication.