DIFFICULTIES IN THE DIAGNOSTICS OF CREUTZFELDT-JACOB DISEASE (CASE REPORT)

Abstract

Creutzfeldt-Jakob disease (CJD) or transmissible spongiform encephalopathy is a nervous system disease from the group of rare prion neurodegenerative diseases. Accumulation of the pathological form of the specific PrPSc protein leads to the death of nerve cells. These facts, as well as the peculiarities of epidemiology, the absence of specific clinical signs, cause a number of difficulties in the life-time diagnosis of this disease. This article presents a case of probable CJD in a patient of the neurological department for patients with cerebrovascular accidents. One of its possible phenotypic variants is considered. Attention is paid to the difficulties of making a diagnosis.