MODERN ASPECTS OF CHRONIC GENERALIZED PERIODONTITIS ETIOPATHOGENESIS (LITERATURE REVIEW)

Abstract

The article presents a review of the literature data on the investigation of chronic generalized periodontitis etiopathogenesis. Despite the large number of research papers on this issue, today the role of some varieties of microorganisms in the development of a generalized process of inflammation and destruction in periodontium is not sufficiently established. The interactions between lipid and protein peroxidation and the antioxidant system in case of periodontitis are not well understood. There is practically no data on the contribution of changes in functional, metabolic activity and features of the implementation of programmed death of inflammatory effector cells, in particular blood neutrophils in the pathogenesis of periodontitis. Information on how the dysfunction of the nitrogen (II) oxide system and hydrogen sulfide affect periodontal disease is contradictory. Therefore, further studies aimed to investigate the etiopathogenesis of chronic generalized periodontitis are relevant and promising.