THE ROLE OF OPPORTUNISTIC MICROORGANISMS IN THE DEVELOPMENT OF PURULENT-NECROTIC COMPLICATIONS IN PATIENTS WITH DIABETIC FOOT SYNDROME

Abstract

The article presents a study investigating the microbial composition and antibiotic susceptibility of microorganisms isolated from purulent-necrotic infections in patients with diabetic foot syndrome, a severe complication of diabetes mellitus. The study aimed to identify the species of conditionally pathogenic microbiota involved in these infections and assess their antibiotic resistance profiles. Bacteriological analysis was performed on samples obtained from 51 patients, and the antibiotic susceptibility of the isolated microorganisms was evaluated. The results revealed the presence of various microorganisms, including Staphylococcus aureus (42.8%), Klebsiella spp. (21%), Pseudomonas aeruginosa (9.8%), and Candida fungi (10.4%). The findings indicate that diabetic foot syndrome has a polymicrobial etiology, with the causative agents exhibiting multidrug resistance. The predominant pathogens identified were S. aureus and Klebsiella spp. The study underscores the importance of analyzing the microbial composition of infection sites and their antibiotic susceptibility patterns, as this knowledge can contribute to optimizing antibacterial therapy, enhancing treatment efficacy, and reducing the risk of lower limb amputations.