REPRODUCTIVE HEALTH AND VITAMIN D3 STATUS OF ADOLESCENT GIRLS WITH OVERWEIGHT AND OBESITY

Abstract

The results of a study to determine indicators of reproductive health and vitamin D sufficiency in overweight and obese adolescent girls are presented.
The study involved 76 adolescent girls aged 13-16 years and was divided into 3 groups according to body mass index (BMI). Group I included 29 overweight adolescents, group II included 27 obese girls, and group III included 20 healthy adolescent girls with normal body weight. The examination included: examination, analysis of the medical history, evaluation of physical and sexual development, determination of BMI, transabdominal ultrasound examination of female pelvis, determination of the level of luteotropin (LH) and folliculotropin (FH), estradiol, testosterone, level 25-(OH)-D3, total and ionized serum calcium in blood serum.
Menstrual dysfunction structural changes in the ovaries according to ultrasound data were significantly more common in overweight and obese girls. Changes in hormonal status were significantly more often diagnosed in the group of girls with obesity, as well as changes were detected in the group of girls with overweight. Girls in all groups had manifestations of vitamin D deficiency or insufficiency, with lower rates in the group of obese girls. Adolescent girls with overweight or obesity are more likely to experience menstrual irregularities in the form of oligo- and dysmenorrhea, which is accompanied by structural changes in the ovaries.