INFLUENCE OF ANTI-ENDOMETRIAL ANTIBODIES ON THE ACTIVITY OF INFLAMMATORY PROCESSES IN PATIENTS WITH GENITAL ENDOMETRIOSIS

Abstract

The article provides information on the correlation between autoimmune processes and inflammation mediators in women with genital endometriosis. 100 reproductive age women with genital endometriosis were included in present study. We have determined the levels of TNF-α as anti-inflammatory cytokine and antiendometrial antibodies (AEA) in peripheral blood serum of women by standard ELISA method. Increased inflammation stimulates the synthesis of autoimmune antibodies in women with genital endometriosis. It was detected statistically significant positive correlation between AEA and TNF-α in women with genital endometriosis (p<0.05).